Exposure to metals and metalloids among pregnant women from Spain: Levels and associated factors

• DOI: 10.1016/j.chemosphere.2021.131809
• Publication Date: 2021-08-06T12:31:13Z
• Authors: Manuel Lozano; Mario Murcia; Raquel Soler-Blasco; Maribel Casas; Begotxu Zubero; Gabriel Riutort-M...; Fernando Gil; Pablo Olmedo; Joan O. Grimalt; Rubén Amorós; Aitana Lertxundi; Martine Vrijheid; Ferran Ballester; Sabrina Llop
• Keywords: Metalloid

Humans are regularly exposed to metals and metalloids present in air, water, food, soil domestic materials. Most of them can cross the placental barrier cause adverse impacts on developing foetus.To describe prenatal concentrations study associated sociodemographic, environmental dietary factors pregnant Spanish women.Subjects were 1346 women INMA Project, for whom following arsenic (As), cadmium (Cd), cobalt (Co), copper (Cu), molybdenum (Mo), nickel (Ni), lead (Pb), antimony (Sb), selenium (Se), thallium (Tl) zinc (Zn) determined urine, at both first third trimesters gestation. Sociodemographic, information was collected through questionnaires during pregnancy. Multiple linear mixed models built order association between each metal metalloid factors.The most detected compounds As, Co, Mo, Sb, Se Zn trimesters. element found highest Tl lowest concentrations. We observed significant associations Cd, Cu, working situation, social class age. Seafood, meat, fruits, nuts, vegetables alcohol intake affected levels all but Cd Cu. Proximity industrial areas, fields air pollution related except Sb Se.This is large prospective longitudinal exposure pregnancy include several cohorts Spain. The shows that some modifiable lifestyles, food intakes could be with metal(loid)s, which may considered further studies assess their relationship neonatal health outcomes.