Phase angle values and ultra-processed food consumption are associated with changes in oxidative stress in inflammatory bowel disease patients

• DOI: 10.1016/j.clnesp.2023.06.006
• Publication Date: 2023-06-10T18:40:41Z
• Authors: Juliana Soares Se...; Vilk Jane da Silv...; Pedro Henrique Mo...; Brenda Lois Barro...; Alda Cássia Alves...; Kelly Beatriz Vie...; Mayara Storel Bez...; Poliana Cristina ...; Nadir do Nascimen...; José Miguel Luz P...; Murilo Moura Lima; Armênio Aguiar do...; Moisés Tolentino ...
• Keywords: Malondialdehyde; Bioelectrical Impedance Analysis

Changes in dietary habits including increased intake of refined sugars and fats decreased fiber have been suggested as potential risk factors for the development inflammatory bowel diseases (IBD). Bioelectrical impedance analysis-derived phase angle (PhA) has gaining attention clinical evaluation nutritional status. In this study, we first time investigated relationship PhA ultra-processed food with oxidative stress, body composition biochemical parameters adult patients IBD.Body were evaluated through electrical bioimpedance. Nitrite (Nox), myeloperoxidase (MPO), glutathione (GSH), malondialdehyde (MDA) superoxide dismutase (SOD) levels determined both groups. Food consumption was obtained by a frequency questionnaire (FFQ).In comparison control group, IBD group had (p < 0.05) concentrations Nox (19.95 ± 1.4 vs. 35.43 7.7 μM), MDA (0.70 0.31 4.56 0.62 nmol/L), GSH (9.35 0.38 10.74 0.51 mg NPSH/μL plasma). positively correlated (R2:0.22; p:0.02) SOD (R2:0.25; p:0.01). ingested higher amounts foods (IBD:17.04 2.76 Control:24.88 2.30%). However, better unprocessed or minimally processed (IBD:79.06 3.07 Control:67.83 2.32%). We found positive correlation between (R2 0.43; p:0.01).PhA may be practical effective measure follow-up patients, being associated bilirubin antioxidant enzymes. Also, recommend evaluating foods, since related increasing stress markers patients.