Modulation of faecal miRNAs highlights the preventive effects of a Mediterranean low-inflammatory dietary intervention

• DOI: 10.1016/j.clnu.2024.02.023
• Publication Date: 2024-02-26T06:59:17Z
• Authors: Oscar Illescas; Giulio Ferrero; Antonino Belfiore; Barbara Pardini; Sonia Tarallo; Chiara M. Ciniselli; Sara Noci; Elena Daveri; Stefano Signoroni; Laura Cattaneo; Andrea Mancini; Daniele Morelli; Massimo Milione; Francesca Cordero; Licia Rivoltini; Paolo Verderio; Patrizia Pasanisi; Marco Vitellaro; Alessio Naccarati; Manuela Gariboldi
• Keywords: Mediterranean Diet; Inflammatory Bowel Diseases; Inflammatory response

Dietary interventions have been proposed as therapeutic approaches for several diseases, including cancer. A low-inflammatory Mediterranean dietary intervention, conducted a pilot study in subjects with Familial Adenomatous Polyposis (FAP), reduced markers of local and systemic inflammation. We aim to determine whether this diet may modulate faecal microRNA (miRNA) gene expression the gut.