A prospective international Aspergillus terreus survey: an EFISG, ISHAM and ECMM joint study

• DOI: 10.1016/j.cmi.2017.04.012
• Publication Date: 2017-04-13T12:15:24Z
• Authors: B. Risslegger; T. Zoran; M. Lackner; M. Aigner; F. Sánchez-Reus; A. Rezusta; A. Chowdhary; S.J. Taj-Aldeen; M.C. Arendrup; S. Oliveri; D.P. Kontoyiannis; A. Alastruey-Izqu...; K. Lagrou; G. Lo Cascio; J.F. Meis; W. Buzina; C. Farina; M. Drogari-Apiran...; A. Grancini; A.M. Tortorano; B. Willinger; A. Hamprecht; E. Johnson; L. Klingspor; V. Arsic-Arsenijevic; O.A. Cornely; J. Meletiadis; W. Prammer; V. Tullio; J.-J. Vehreschild; L. Trovato; R.E. Lewis; E. Segal; P.-M. Rath; P. Hamal; M. Rodriguez-Igle...; E. Roilides; S. Arikan-Akdagli; A. Chakrabarti; A.L. Colombo; M.S. Fernández; M.T. Martin-Gomez; H. Badali; G. Petrikkos; N. Klimko; S.M. Heimann; J. Houbraken; O. Uzun; M. Edlinger; S. de la Fuente; C. Lass-Flörl
• Keywords: Aspergillus terreus; Species complex

A prospective international multicentre surveillance study was conducted to investigate the prevalence and amphotericin B susceptibility of Aspergillus terreus species complex infections.A total of 370 cases from 21 countries were evaluated.The overall prevalence of A. terreus species complex among the investigated patients with mould-positive cultures was 5.2% (370/7116). Amphotericin B MICs ranged from 0.125 to 32 mg/L, (median 8 mg/L).Aspergillus terreus species complex infections cause a wide spectrum of aspergillosis and the majority of cryptic species display high amphotericin B MICs.