Clinical neurophysiology of REM parasomnias: Diagnostic aspects and insights into pathophysiology

• DOI: 10.1016/j.cnp.2023.10.003
• Publication Date: 2024-01-10T02:47:13Z
• Authors: Melanie Bergmann; Birgit Högl; Ambra Stefani
• Keywords: Parasomnia; Clinical neurophysiology; K-complex; Nightmare; Neurophysiology; Restless Legs Syndrome; Sleep spindle

Parasomnias are due to a transient unstable state dissociation during entry into sleep, within or arousal from and manifest with abnormal sleep related behaviors, perceptions, emotions, dreams, autonomic nervous system activity Rapid eye movement (REM) parasomnias include REM behavior disorder (RBD), isolated recurrent paralysis nightmare disorder. Neurophysiology is key for diagnosing these disorders provides insights their pathophysiology. RBD very well characterized neurophysiological point of view, also thank the fact that polysomnography needed diagnosis. Diagnostic criteria provided by American Academy Sleep Medicine video-polysomnography guidelines diagnosis International Behavior Disorder Study Group. Differences between two sets presented discussed. Availability in data on electroencephalography (EEG), electrooculography (EOG) electromyography (EMG). EEG shows e.g. changes delta theta power, spindles K complexes. EMG essential an important neurodegeneration biomarker. patients present alterations wake EEG, function, evoked potentials, transcranial magnetic stimulation. Clinical scant. The few available provide pathophysiology disorders, demonstrating suggesting macro- microstructure as