Dosimetric analysis of 17 cardiac Sub-structures, Toxicity, and survival in ultra central lung tumor patients treated with SBRT

• DOI: 10.1016/j.ctro.2023.100675
• Publication Date: 2023-09-14T01:37:49Z
• Authors: Maiwand Ahmadsei; Kai Thaler; Elena Gasser; Bertrand Pouymayou; Riccardo Dal Bello; Sebastian M. Christ; Jonas Willmann; Boldizsar Kovacs; Panagiotis Balermpas; Stephanie Tanadin...; Ardan M. Saguner; Michael Mayinger; Nicolaus Andratschke; Matthias Guckenbe...
• Keywords: Cardiac toxicity; Pulmonary toxicity

•Data on cardiac toxicity after SBRT for ultra-central lung tumors remains limited.•We analyzed the dose to 18 sub-structures and cardiovascular toxicity.•A regimen of 45 Gy in 8-10 fractions yields good local control low toxicity.•The highest doses were observed pulmonary artery left atrium.•Higher base heart seem be associated with non-cancer deaths.