In regard to Kim et al

• DOI: 10.1016/j.ctro.2024.100775
• Publication Date: 2024-03-31T14:10:02Z
• Authors: Tooba Ali; Mariam Hina; Laraib Khan; Bilal Mazhar Qureshi; Asim Hafiz; Ahmed Nadeem Abbasi
• Keywords: Prolongation; Medical physics. Medical radiology. Nuclear medicine; Oncology; Radiation Medicine; Correspondence; Radiation Oncology; R895-920; Neoplasms. Tumors. Oncology. Including cancer and carcinogens; Head and neck radiation; Radiology; Treatment gaps; RC254-282

Our team conceptually aligns with Kim et al.'s original article on "The impact of national holiday post-operative radiotherapy squamous cell carcinoma head and neck" [[1]Kim M.S. Sheridan M. Rajaraman Hollenhorst H. Caissie A. Mahmoud-Ahmed al.The holidays postoperative the neck.Clin Transl Radiat Oncol. 2023 Sep; 1100668Google Scholar], this paper highlights detrimental that have local control in neck radiation. This study unequivocally demonstrates 15.4 % risk recurrence at five years (p value: 0.017) due to influence. matter is a stumbling point patient centered management for our patients, specifically Low- Middle-Income Countries (LMIC). It very frequent these regions allocate four treatment gaps accommodate public holidays, practice markedly affects as emphasized your published article. Furthermore, Ferreira al. any extension duration results progressive decline ranging from 1 1.2 per day high 12–14 week [[2]Ferreira J.A. Olasolo J.J. Azinovic I. Jeremic B. Effect delay overall time survival cancer: review literature.Rep Pract Oncol Radiother. 2015; 20: 328-339Crossref PubMed Scopus (98) Google Scholar]. would humbly request authors add their inferences gained observations gathered other types RT gaps, which occurred causes than holidays. LMIC we wish make some comments strategy pertinent discussion all cases Multidisciplinary Tumor board meetings [[3]Abbasi A.N. Karim M.U. Ali N. Hafiz Qureshi B.M. tumour boards are lifeline cancer patients lower middle income countries.Clin 2016 Dec 1; 28: 799Abstract Full Text PDF Scholar] intradisciplinary peer meetings, two processes help ensuring quality radiation appropriate delivery prescribed sessions without [[4]Qureshi Mansha M.A. Mirkhan al.Impact planning process: experience tertiary care university hospital Pakistan.J Global 2019 Aug; 5: 1-7PubMed In Yao about locally advanced nasopharyngeal carcinoma, they delineated Radiotherapy Interruption (RTI) deviation between actual taken complete therapy originally planned duration. Their findings indicated an RTI exceeding 5.5 days significantly correlated reduced capacity achieving favorable outcomes. At 5 specifically, who adhered designated schedule achieved impressive loco regional free rate 97 %, contrary those experienced interruptions lasting more days, among whom dropped notably 83 (p-value 0.001).[[5]Yao Jin Y.N. Wang S.Y. Zhang F. Zhou G.Q. W.J. effects interruption after concurrent chemoradiotherapy T-stage carcinoma: observational, prospective analysis.BMC Cancer. 2018 Dec; 18: 1-7Crossref (31) Dale effect unscheduled prolongation or dire need preemptively identify expected breaks resulting was suggested compensate by scheduling them weekends. Extensive knowledge radiobiological behavior can further modify assist compensating [[6]Dale R.G. Hendry J.H. Jones Robertson A.G. Deehan C. Sinclair Practical methods missed radiotherapy, particular reference schedules.Clin 2002 Oct 14: 382-393Abstract (0) Moreover machine breakdown, twin LINAC installment mandated ensure uninterrupted unforeseen technical issues, similar substitute re plan complex VMAT/IMRT [[7]Treutwein M, Härtl PM, Gröger C, Katsilieri Z, Dobler Linac twins radiotherapy. Evolution Ionizing Radiation Research. Rijeka: InTech. 2015 Sep 17:171-86.Google We agree early recognition development need-based schedules timing paramount importance. The declare no known competing financial interests personal relationships could appeared influence work reported paper.