Navigating practical challenges in immunotherapy for metastatic triple negative breast cancer

• DOI: 10.1016/j.ctrv.2024.102762
• Publication Date: 2024-05-16T07:06:56Z
• Authors: Luca Licata; Maria Vittoria Dieci; Carmine De Angelis; Caterina Marchiò; Federica Miglietta; Laura Cortesi; Alessandra Fabi; Peter Schmid; Javier Cortes; Lajos Pusztai; Giampaolo Bianchini; Giuseppe Curigliano
• Keywords: Triple-negative breast cancer; Cancer Immunotherapy

Immunotherapy has revolutionized cancer therapy and now represents a standard of care for many tumor types, including triple-negative breast cancer. Despite the positive results that have led to approval immunotherapy in both early- advanced-stage cancer, pivotal clinical trials cannot address myriad questions arising everyday practice, often falling short delivering all information clinicians require. In this manuscript, we aim some these practical questions, with purpose providing guide optimizing use immune checkpoint inhibitors management patients identifying opportunities future research clarify unresolved questions.