Socioeconomic resources are associated with distributed alterations of the brain’s intrinsic functional architecture in youth

• DOI: 10.1016/j.dcn.2022.101164
• Publication Date: 2022-10-17T07:28:20Z
• Authors: Chandra Sripada; Arianna M. Gard; Mike Angstadt; Aman Taxali; Tristan Greathouse; Katherine McCurry; Luke W. Hyde; Alexander Weigard; Peter Walczyk; Mary Heitzeg
• Keywords: Human Connectome Project; Typically developing

Little is known about how exposure to limited socioeconomic resources (SER) in childhood gets "under the skin" shape brain development, especially using rigorous whole-brain multivariate methods large, adequately powered samples. The present study examined resting state functional connectivity patterns from 5821 youth Adolescent Brain Cognitive Development (ABCD) study, employing across three levels: whole-brain, network-wise, and connection-wise. Across all levels, SER was associated with widespread alterations connectome. However, critically, we found that parental education primary driver of neural associations SER. These developing connectome exhibited notable concentrations somatosensory subcortical regions, they were partially accounted for by home enrichment activities, child's cognitive abilities, grades, indicating interwoven links between education, child stimulation, performance. results add a new data-driven, perspective on household