In vitro antimicrobial activity of rifaximin against enteropathogens causing traveler's diarrhea

• DOI: 10.1016/j.diagmicrobio.2007.07.003
• Publication Date: 2007-10-02T14:56:04Z
• Authors: Joaquim Ruiz; Laura Mensa; Cristina O'Callaghan; Maria J. Pons; Ana González; Jordi Vila; Joaquim Gascón
• Keywords: Rifaximin; Traveler's diarrhea

The in vitro activity of rifaximin against 84 diarrheagenic Escherichia coli and 11 Shigella sonnei causing traveler's diarrhea was evaluated. The MIC of rifaximin ranged between <0.007 and 32 mg/L; other agents tested had an MIC of >256 mg/L in most cases. The results showed the potential use of rifaximin to treat these infections.