Multidrug-resistant gram-negative bacilli colonization risk factors among trauma patients

• DOI: 10.1016/j.diagmicrobio.2015.12.014
• Publication Date: 2015-12-23T03:46:49Z
• Authors: Laura J. Gilbert; Ping Li; Clinton K. Murray; Heather C. Yun; Deepak Aggarwal; Amy C. Weintrob; David R. Tribble
• Keywords: Cefazolin; Gram-Negative Bacteria

Prior studies have demonstrated high rates of colonization and infection with multidrug-resistant gram-negative bacilli (MDR-GNB) in injured military personnel. Our analysis shows that injuries inflicted during peak combat periods, massive blood transfusion requirement, and posttrauma cefazolin prophylaxis (additive effect with fluoroquinolones) were risk factors for MDR-GNB colonization.