Genomic characteristics of listeria monocytogenes causing invasive listeriosis in Japan

• DOI: 10.1016/j.diagmicrobio.2020.115233
• Publication Date: 2020-10-06T02:35:05Z
• Authors: Hiroaki Baba; Hajime Kanamori; Risako Kakuta; Hiroki Sakurai; Kengo Oshima; Tetsuji Aoyagi; Mitsuo Kaku
• Keywords: Adult; Aged, 80 and over; Male; 0301 basic medicine; Whole Genome Sequencing; Virulence Factors; Age Factors; Infant; Genomics; Listeria monocytogenes; 3. Good health; 03 medical and health sciences; Bacterial Proteins; Japan; Humans; Female; Listeriosis; Genome, Bacterial; Aged

We reviewed 18 listeriosis cases in Japan and performed molecular analysis of causative Listeria monocytogenes (LM) isolates. Strains genetically related to those from other countries caused various types of listeriosis, including vascular listeriosis in immunocompetent elderly people. Our results highlight the importance of integrated clinical and genomic analysis of LM.