Data highlighting phenotypic diversity of urine-associated Escherichia coli isolates

• DOI: 10.1016/j.dib.2020.105811
• Publication Date: 2020-06-03T23:37:10Z
• Authors: Allison R. Eberly; Connor J. Beebout; Ching Man Carmen ...; Gerald T. Van Horn; Hamilton D. Green; Madison J. Fitzge...; Shuvro De; Emily K. Apple; Alexandra C. Schr...; Simona G. Codreanu; Stacy D. Sherrod; John A. McLean; Douglass B. Clayton; Charles W. Stratton; Jonathan E. Schmitz; Maria Hadjifrangi...
• Keywords: Urinary tract infection; 0303 health sciences; Science (General); Biofilm; Computer applications to medicine. Medical informatics; R858-859.7; 3. Good health; Q1-390; 03 medical and health sciences; Biochemistry, Genetics and Molecular Biology; Cystitis; Metabolomics; Uropathogenic Escherichia coli; Asymptomatic bacteriuria

This article provides a reusable dataset describing detailed phenotypic and associated clinical parameters in n=303 clinical isolates of urinary Escherichia coli collected at Vanderbilt University Medical Center. De-identified clinical data collected with each isolate are detailed here and correlated to biofilm abundance and metabolomics data. Biofilm-abundance data were collected for each isolate under different in vitro conditions along with datasets quantifying biofilm abundance of each isolate under different conditions. Metabolomics data were collected from a subset of bacterial strains isolated from uncomplicated cases of cystitis or cases with no apparent symptoms accompanying colonization. For more insight, please see "Defining a Molecular Signature for Uropathogenic versus Urocolonizing Escherichia coli: The Status of the Field and New Clinical Opportunities" [1].