Management of Helicobacter pylori infection: Guidelines of the Italian Society of Gastroenterology (SIGE) and the Italian Society of Digestive Endoscopy (SIED)

• DOI: 10.1016/j.dld.2022.06.019
• Publication Date: 2022-07-10T11:04:30Z
• Authors: Marco Romano; Antonietta Gerard...; Leonardo Henry Eu...; Raffaele Pellegrino; Giovanna Palladino; Leonardo Frazzoni; Elton Dajti; Antonio Gasbarrini; Francesco Di Mario; Rocco Maurizio Za...; Antonio Benedetti; Bruno Annibale; Patrizia Burra; Marcello Fabio Maida; Francesco Luzza; Luigi Ricciardiello; Maurizio Vecchi; Luca Frulloni; Alessandro Repici; Edoardo Vincenzo ...; Luigi Pasquale; Antonio Pisani; Antonietta Lamazza; Gianpaolo Cengia; Enrico Ciliberto; Rita Luisa Conigl...; Paola Da Massa Ca...; Bastianello Germanà
• Keywords: Helicobacter

Helicobacter pylori infection is very common and affects more than one-third of adults in Italy. Helicobacter pylori causes several gastro-duodenal diseases, such as gastritis, peptic ulcer and gastric malignancy, and extra-gastric diseases. The eradication of the bacteria is becoming complex to achieve due to increasing antimicrobial resistance. To address clinical questions related to the diagnosis and treatment of Helicobacter pylori infection, three working groups examined the following topics: (1) non-invasive and invasive diagnostic tests, (2) first-line treatment, and (3) rescue therapies for Helicobacter pylori infection. Recommendations are based on the best available evidence to help physicians manage Helicobacter pylori infection in Italy, and have been endorsed by the Italian Society of Gastroenterology and the Italian Society of Digestive Endoscopy.