Pan-cancer analysis of antibody-drug conjugate targets and putative predictors of treatment response

• DOI: 10.1016/j.ejca.2023.113379
• Publication Date: 2023-10-11T22:11:20Z
• Authors: Carlo Bosi; Áron Bartha; Barbara Galbardi; Giulia Notini; Matteo M. Naldini; Luca Licata; Giulia Viale; Marco Mariani; Barbara Pistilli; H. Raza Ali; Fabrice André; Marta Piras; Maurizio Callari; Marco Barreca; Alberta Locatelli; Lucia Viganò; Carmen Criscitiello; Lajos Pusztai; Giuseppe Curigliano; Balázs Győrffy; Matteo Dugo; Giampaolo Bianchini
• Keywords: Antibody-drug conjugate

Antibody-drug conjugates (ADCs) are a rapidly expanding class of compounds in oncology. Our goal was to assess the expression ADC targets and potential downstream determining factors activity across pan-cancer normal tissues.