Investigating novel thiazolyl-indazole derivatives as scaffolds for SARS-CoV-2 MPro inhibitors

• DOI: 10.1016/j.ejmcr.2022.100034
• Publication Date: 2022-02-10T03:01:22Z
• Authors: Justin Airas; Catherine A. Bayas; Abdellah N'Ait Ou...; Moulay Youssef Ai...; Aziz Auhmani; Mohamed Loubidi; M'hamed Esseffar; Julie A. Pollock; Carol A. Parish
• Keywords: Docking (animal); Linker

COVID-19 is a global pandemic caused by infection with the SARS-CoV-2 virus. Remdesivir, RNA polymerase inhibitor, only drug to have received widespread approval for treatment of COVID-19. The main protease enzyme (M