Dynamic Hepatocellular Carcinoma Model Within a Liver Phantom for Multimodality Imaging

• DOI: 10.1016/j.ejro.2020.100257
• Publication Date: 2020-09-03T11:46:52Z
• Authors: Muntaser S. Ahmad; Nursakinah Suardi; Ahmad Shukri; Nik Noor Ashikin ...; Ammar A. Oglat; Osama Makhamrah; Hjouj Mohammad
• Keywords: Multimodality

IntroductionHepatocellular carcinoma (HCC) is one of the most common cancer in world, and effectiveness its treatment lies detection early stages. The aim this study to mimic HCC dynamically through a liver phantom apply it multimodality medical imaging techniques including magnetic resonance (MRI), computed tomography (CT), ultrasound.Methods materialsThe fabricated with two main parts, parenchyma inserts. was by adding 2.5 wt% agarose powder combined 2.6 wax while basic material for samples made from polyurethane solution 5 glycerol. Three were inserted into using three cylinders implanted inside parenchyma. An automatic injector attached input side suction device connected output cylinders. After prepared, contrast materials injected imaged MRI, CT, ultrasound.ResultsBoth clearly distinguished modalities: ultrasound. Doppler ultrasound also applied flow pattern observed samples.ConclusionA multimodal dynamic phantom, tumor models have been fabricated. This helps improve develop different methods detecting