Simultaneous assessment of heart and lungs with gated high-pitch ultra-low dose chest CT using artificial intelligence-based calcium scoring

• DOI: 10.1016/j.ejro.2023.100481
• Publication Date: 2023-02-15T06:29:51Z
• Authors: Florian Andre; Sebastian Seitz; Philipp Fortner; Thomas Allmendinger; André Sommer; Matthias Brado; Roman Sokiranski; Joana Fink; Hans-Ulrich Kauczor; Claus P. Heussel; Felix Herth; Norbert Frey; Johannes Görich; Sebastian J. Buss
• Keywords: Agatston score; Coronary Calcium Score

The combined testing for coronary artery and pulmonary diseases is of clinical interest as risk factors are shared. In this study, a novel ECG-gated tin-filtered ultra-low dose chest CT protocol (GCCT) integrated heart lung acquisition the applicability artificial intelligence (AI)-based calcium scoring were assessed.In registry 10481 patients undergoing CT, GCCT was applied in 44 on dual-source CT. Coronary scans (CCS) with 120 kVp, 100 kVp (Sn100) controls, matched regard to age, sex, body-mass index, retrieved from (ntotal=176, 66.5 (59.4-74.0) years, 52 men). Automatic tube current modulation used all scans. 20 Sn100 CCS, Agatston scores measured both semi-automatically by experts AI, classified into six groups (0, <10, <100, <400, <1000, ≥1000).Effective decreased significantly CCS (0.50 (0.41-0.61) mSv) (0.34 (0.26-0.37) (0.14 (0.11-0.17) mSv). showed higher values (0.28 (0.21-0.32) than but lower (all p < 0.05) despite greater scan length. correlated strongly between semi-automatic AI-based measurements (both ρ = 0.98, 0.001) resulting high agreement score classification (κ 0.97, 95% CI 0.92-1.00; κ 0.89, 0.79-0.99). Regarding findings, further diagnostic steps recommended 28 patients.GCCT allows reliable disease cancer screening radiation exposure. GCCT-derived shows excellent standard equivalent stratification.