WCN24-1327 EFFECTS OF PHOTOBIOMODULATION ON RENAL FUNCTION IN RATS WITH DIABETIC KIDNEY DISEASE

• DOI: 10.1016/j.ekir.2024.02.466
• Publication Date: 2024-04-03T10:11:15Z
• Authors: Garcia Villalba; Eloiza de Oliveira; Carla Djamila; Guilherme Ferreira; Alessandra Oliveira; Juliana veloso; Maikol Lucas; Bryan Gonzales; Camila Lima; Maria de Fátima V...

Diabetic kidney disease (DKD) is one of the most serious microangiopathic complications diabetes mellitus (DM). Evidences suggest that hemodynamic changes and cellular metabolism are related to pathogenesis chronic (CKD), including mitochondrial dysfunction, oxidative stress, inflammation dysregulation intestinal microbiotal.1,2 Photobiomodulation therapy (PBM) a non-pharmacological uses red infrared spectral range light, with wavelength 450 1100nm, trigger photochemical within extracellular intracellular structures, without heat release or negligible thermal release.3,4 Pre-clinical clinical studies in rat model CKD induced by metabolic syndrome showed reduced blood pressure, increased glomerular filtration rate decreased tubulointerstitial fibrosis.2 after photobiomodulation.