Association of short-term exposure to ambient PM1 with total and cause-specific cardiovascular disease mortality

• DOI: 10.1016/j.envint.2022.107519
• Publication Date: 2022-09-16T06:37:23Z
• Authors: Ruijun Xu; Jing Wei; Tingting Liu; Yingxin Li; Chunyu Yang; Chunxiang Shi; Gongbo Chen; Yun Zhou; Hong Sun; Yuewei Liu
• Keywords: Stroke

The acute effects of exposure to ambient particulate matter with an aerodynamic diameter ≤1 μm (PM1) on cardiovascular disease (CVD) mortality remain unclear. To investigate whether short-term PM1 was associated from total and/or cause-specific CVDs, and estimate the excess mortality. A time-stratified case-crossover study conducted among 1,081,507 CVD deaths in Jiangsu province, China 2015 2020. We assessed daily residential exposures using a validated grid dataset for each subject. Conditional logistic regression models distributed lag linear or nonlinear were employed quantify association during same day death 1 prior. Each 10 μg/m3 increase significantly 1.46 % (95 confidence interval: 1.28 %, 1.65 %), 1.95 (1.28 2.63 1.16 (0.86 1.47 1.41 (1.13 1.69 1.83 (1.37 2.30 %) increased odds hypertensive diseases (HDs), ischemic heart (IHDs), stroke, sequelae respectively (all p <0.05). No significant identified pulmonary chronic rheumatic diseases. fraction attributable 5.71 while fractions ranged 4.98 IHDs 7.46 HDs. Significantly higher observed certain adults 80 years older. found that specific CVDs may lead considerable especially older adults. Our findings highlight potential approach prevent premature by reducing provide essential quantitative data development future air quality standards PM1.