Association between fine particulate matter and fecundability in Henan, China: A prospective cohort study

• DOI: 10.1016/j.envint.2024.108754
• Publication Date: 2024-05-21T01:44:16Z
• Authors: Rong Zhang; Jun Zhao; Yue Zhang; Xiang Hong; Hongguang Zhang; Hanyue Zheng; Jingwei Wu; Yuanyuan Wang; Zuoqi Peng; Ya Zhang; Lifang Jiang; Yueshu Zhao; Qiaomei Wang; Haiping Shen; Yiping Zhang; Donghai Yan; Bei Wang; Xu Ma
• Keywords: Association (psychology)

To investigate the relationship between ambient fine particulate matter (PM2.5) exposure and fecundability. This study included 751,270 female residents from Henan Province who participated in National Free Pre-conception Check-up Projects during 2015–2017. Ambient cycle-specific PM2.5 was assessed at county level for each participant using satellite-based concentration data 1-km resolution. Cox proportional hazards models with time-varying were used to estimate association fecundability exposure, adjusted potential individual risk factors. During period, 568,713 participants pregnant, monthly mean concentrations varied 25.5 114.0 µg/m3 across areas. For 10 increase PM2.5, hazard ratio 0.951 (95 % confidence interval: 0.950 0.953). The more pronounced women older, urban household registration, history of pregnancy, higher body mass index (BMI), hypertension, without tobacco, or whose male partners BMI, hypertension. In this population-based prospective cohort, associated reduced These findings may support adverse implications severe air pollution on reproductive health.