Effects of ciprofloxacin, trimethoprim, and amoxicillin on microbial structure and growth as emerging pollutants reaching crop soils

• DOI: 10.1016/j.envres.2022.113916
• Publication Date: 2022-07-21T02:15:34Z
• Authors: Laura Rodríguez-G...; Avelino Núñez-Del...; Esperanza Álvarez...; Elena García-Campos; Ángela Martín; Montserrat Díaz-R...; Manuel Arias-Estévez; David Fernández-C...; Vanesa Santás-Miguel
• Keywords: Trimethoprim

The presence of emerging pollutants, and specifically antibiotics, in agricultural soils has increased notably recent decades, causing growing concern as regards potential environmental health issues. With this mind, the current study focuses on evaluating toxicity exerted by three antibiotics (amoxicillin, trimethoprim, ciprofloxacin) growth soil bacterial communities, when these pollutants are present at different doses, considered short, medium, long terms (1, 8 42 days incubation). Specifically, research was carried out 12 having physicochemical characteristics performed means leucine (3H) incorporation method. In addition, changes structure microbial communities were studied four soils, using phospholipids fatty acids method for this. main results indicate that most toxic antibiotic amoxicillin, followed trimethoprim ciprofloxacin. also show amoxicillin decreases with time, values Log IC50 ranging from 0.07 ± 0.05 to 3.43 0.08 day 1, 0.95 3.97 0.15 8, 2.05 0.03 3.18 0.04 42, during incubation period. Regarding 3 behaviors observed: some not affected, a second group showed dose-response effects remained persistent over and, finally, third being greater longer times (42 days). As ciprofloxacin, did effect any or studied. Furthermore, principal component analysis demonstrated community which persisted after incubation, depended mainly lesser extent, dose type ciprofloxacin). it found that, research, application usually favored fungi Gram-positive bacteria.