FRU (BHLH029) is required for induction of iron mobilization genes in Arabidopsis thaliana

• DOI: 10.1016/j.febslet.2004.10.062
• Publication Date: 2004-11-05T18:00:12Z
• Authors: Marc Jakoby; Hong-Yu Wang; Wim Reidt; Bernd Weisshaar; Petra Bauer
• Keywords: Iron; Molecular Sequence Data; Arabidopsis; Mobilization; Genes, Plant; Plant Roots; 03 medical and health sciences; bHLH; Gene Expression Regulation, Plant; Genes, Regulator; Basic Helix-Loop-Helix Transcription Factors; Amino Acid Sequence; Promoter Regions, Genetic; Molecular Biology; Conserved Sequence; 2. Zero hunger; 0303 health sciences; Arabidopsis Proteins; Reverse Transcriptase Polymerase Chain Reaction; Helix-Loop-Helix Motifs; Plant; Iron Deficiencies; Plants, Genetically Modified; Protein Structure, Tertiary; Root; Genetic Techniques; Mutation

Iron mobilization responses are induced by low iron supply at transcriptional level. In tomato, the basic helix‐loop‐helix gene FER is required for induction of mobilization. Using molecular‐genetic techniques, we analyzed function BHLH029 , named FRU ( ‐like regulator uptake), Arabidopsis thaliana homolog tomato gene. The was mainly expressed in roots a cell‐specific pattern and deficiency. mutant plants were chlorotic, found necessary essential genes FRO2 (ferric chelate reductase gene) IRT1 (iron‐regulated transporter gene). Overexpression resulted an increase supply. Thus, mediator indicating that regulation uptake conserved dicot species.