Thermodynamics of phase transfer for polar molecules from alkanes to deep eutectic solvents

• DOI: 10.1016/j.fluid.2017.05.008
• Publication Date: 2017-05-06T18:47:15Z
• Authors: Andrew P. Abbott; Azhar Y.M. Al-Mur...; Odeh A.O. Alshammari; Robert C. Harris; Jalil H. Kareem; Idrees B. Qader; Karl Ryder
• Keywords: Endothermic process

Abstract Deep eutectic solvents (DESs) have been used for the purification of oils and the extraction of active ingredients from natural products but little is known about the mechanism of the extraction process. In this study a variety of molecular solutes are dissolved in alkanes and the thermodynamics of transfer into six DESs have been quantified. It is shown that the transfer of most solutes into the DES is endothermic and driven by entropy. The largest partition coefficients were demonstrated by the liquids with the lowest surface tensions and this is thought to arise because the enthalpy of hole formation controls the rate of solute transfer. Accordingly, it was shown that the size of the solute has an effect on the partition coefficient with smaller solutes partitioning preferably into the DES. As expected, solutes capable of strongly hydrogen bonding partitioned much better into the DES as the enthalpy of transfer was negative.