Impact of SARS-CoV-2 infection in pregnant women and their babies: clinical and epidemiological features

• DOI: 10.1016/j.gaceta.2023.102332
• Publication Date: 2023-11-25T23:12:10Z
• Authors: María José Vidal; Èrica Martínez-So...; Sergi Mendoza; Núria Sala; Mireia Jané; Jacobo Mendioroz; Pilar Ciruela
• Keywords: Pregnancy outcomes; COVID-19 Vaccines; SARS-CoV-2; Infant, Newborn; Neonates; Infant; COVID-19; 3. Good health; COVID-19 Testing; Cross-Sectional Studies; Recién nacido; Pregnancy; Humans; Premature Birth; Female; Complicaciones del embarazo; Pregnant Women; Public aspects of medicine; RA1-1270; Pregnancy Complications, Infectious; Premature birth; Nacimiento prematuro; Retrospective Studies

Assess the risk associated with COVID-19 in pregnant women on maternal and neonatal outcomes Catalonia (Spain) 2020, before beginning of vaccination campaign. Cross-sectional descriptive study all (41,560) their live newborns (42,097) (1st March to 31st December 2020). Women were classified: positive negative diagnosis during pregnancy. The analysed complications pregnancy, gestational age, admission intensive care unit (NICU) birth weight. Associations among infant variables measured logistic regression models. Results expressed as odds ratios 95% confidence intervals. Models adjusted for nationality, socioeconomic status, type pregnancy centre where delivery occurred (public or private management hospital). A total 696 (1.7%) diagnosed 4.37 times more likely have (4.37; 3.52-5.40). 713 from mothers COVID-19. increased preterm (1.41; 1.03-1.89), NICU (1.40; 1.06-1.82) low weight (1.35; 0.99-1.80) babies. Pregnant had higher developing be admitted prematurity. Evaluar el riesgo asociado de y los resultados en mujeres embarazadas sus recién nacidos Cataluña (España) antes del inicio la campaña vacunación. Estudio descriptivo transversal gestantes (41.560) (42.097) (del 1 marzo al 31 diciembre Las fueron clasificadas según diagnóstico positivo o negativo durante embarazo. Los analizados complicaciones gestacionales, semana gestacional, ingreso nacido unidad cuidados intensivos neonatales (UCIN) bajo peso nacer. asociaciones entre maternas perinatales se midieron con regresión logística. expresaron ratio e intervalo confianza 95%. modelos ajustaron por nacionalidad, edad materna, nivel socioeconómico, tipo embarazo titularidad (pública privada) hospital donde dio a luz. Un (1,7%) diagnosticadas presentaron 4,37 veces mayor probabilidad tener (4,37; 3,52-5,40). Hubo El incrementó prematuridad (1,41; 1,03-1,89), UCIN (1,40; 1,06-1,82) nacer (1,35; 0,99-1,80) nacidos. desarrollar hijos tuvieron prematuridad.