Effects of atropine 0.01% on refractive errors in children with myopia

• DOI: 10.1016/j.heliyon.2023.e18743
• Publication Date: 2023-07-27T14:27:33Z
• Authors: Xingxue Zhu; Yuliang Wang; Yujia Liu; Chaoying Ye; Xingtao Zhou; Xiaomei Qu
• Keywords: Astigmatism

Little is known about changes in astigmatism during atropine treatment. We aimed to explore the effects of 0.01% eye drops on both spherical and cylindrical refractive errors myopic children.Children aged 6-14 years with myopia ≥ -6.00 D < -0.50 D, total > -2.00 at least one were enrolled. Subjects randomised either receive once nightly single-vision lenses or simply wear followed up 3-month intervals. Cycloplegic refraction axial length measured. The magnitude direction (TA), corneal (CA), residual (RA) evaluated.Overall, 119 eyes (69 group 50 control group) included final analyses after 9 months. Atropine-treated showed significantly less progression than did (spherical equivalent: -0.35 ± 0.33 vs. -0.56 0.49 p = 0.001; length: 0.20 0.19 mm, 0.001). Compared (-0.04 0.23 D), a significant increase TA was observed atropine-treated (-0.14 0.29 D); this mainly attributed CA (-0.17 0.26 D) rather minor decrease RA (0.02 0.32 D).Atropine effective preventing progression, whereas months treatment resulted clinically small, but statistically Chinese children.