Lowered ratio of corticospinal excitation to inhibition predicts greater disability, poorer motor and cognitive function in multiple sclerosis

• DOI: 10.1016/j.heliyon.2024.e35834
• Publication Date: 2024-08-06T07:06:49Z
• Authors: Arthur R. Chaves; Sara Tremblay; Lara Pilutti; Michelle Ploughman
• Keywords: Neurophysiology

Investigate excitatory-inhibitory (E/I) (im)balance using transcranial magnetic stimulation (TMS) in individuals with Multiple Sclerosis (MS) and determine its validity as a neurophysiological biomarker of disability.