Newest therapeutic strategies impacting on rarest thoracic malignancies: The clinical case report of biphasic pleural mesothelioma

• DOI: 10.1016/j.heliyon.2024.e36306
• Publication Date: 2024-08-14T07:10:47Z
• Authors: F. Pellicioli; L. Sala; F. Colonese; E. Belloni; M.I. Abbate; S. Canova; A. D'Agostino; D.L. Cortinovis
• Keywords: Clinical trial; Social sciences (General); H1-99; 0301 basic medicine; Q1-390; 03 medical and health sciences; Science (General); Case report; Case Report; Case report; Clinical trial; Pleural mesothelioma;; Pleural mesothelioma

A caucasian 62-year-old woman, diagnosed with biphasic pleural mesothelioma (PM) of II stage and BAP1 loss, was treated with therapies included in clinical trial and Early Access Programmes (EAP). During her clinical history, radiological images presented an unusual representation of the disease, with a pseudo progression discussed many times by several specialists. The patient's overall survival improved as a result of the multidisciplinary team and the availability of medicines outside of clinical practice.