Long-term effects of ciprofloxacin treatment on the gastrointestinal and oropharyngeal microbiome are more pronounced after longer antibiotic courses

• DOI: 10.1016/j.ijantimicag.2024.107259
• Publication Date: 2024-06-26T06:51:39Z
• Authors: J.P. Rodriguez-Ruiz; Q. Lin; L. Van Heirstraeten; C. Lammens; A.J. Stewardson; M. Godycki-Cwirko; S. Coenen; H. Goossens; S. Harbarth; S. Malhotra-Kumar; Jascha Vervoort; Jean Claude Nguyen; Laurent Gutmann; Niels Adriaessens
• Keywords: 0301 basic medicine; 03 medical and health sciences; Pharmacology. Therapy; Biology

Urinary tract infections (UTIs) are one of the main reasons for antibiotic prescriptions in primary care. Recent studies demonstrate similar clinical outcomes with short vs. long antibiotics courses. The aim this study was to investigate differential collateral effect ciprofloxacin treatment duration on gastrointestinal and oropharyngeal microbiome patients presenting uncomplicated UTI care practices Switzerland, Belgium Poland.