Long-term outcomes following transvenous lead extraction: Data from a tertiary referral center

• DOI: 10.1016/j.ijcard.2023.02.040
• Publication Date: 2023-02-24T13:29:33Z
• Authors: Gianmarco Arabia; Gianfranco Mitacc...; Angelica Cersosimo; Emiliano Calvi; Francesca Salghetti; Luca Bontempi; Daniele Giacopelli; Manuel Cerini; Antonio Curnis
• Keywords: Clinical endpoint; Single Center

Transvenous lead extraction (TLE) has shown a safe and efficacy profile in the intraoperative short-term setting; however, data on long-term outcomes are limited.The purpose of this study was to assess prognostic factors patients who underwent TLE.Consecutive with cardiac implantable electronic device (CIED) TLE between 2014 2016 were retrospectively studied. The primary outcome composite endpoint death repeated stratified by infective/non-infective indication. Individual components also evaluated.One hundred ninety-one included analysis, 50% extracted for CIED-related infection. Complete procedural success achieved 189 (99%) no major acute complications. After median 6.5 years, infection indication associated significantly lower event-free survival (67% vs. 83% non-infection group, adjusted hazard ratio [aHR] 1.97, 95% confidence interval [CI] 1.02-3.81, p = 0.04). All-cause mortality rate higher group (30% 10%, < 0.01). did not differ groups (4% 7%, 0.62). Among had infection, presence vegetation (aHR 2.56; 95%CI 1.17-5.63, 0.02) positive blood cultures 2.64; 1.04-6.70, 0.04) independently outcome.Patients exhibit high risk during follow-up. Vegetation worse prognosis regardless successful uncomplicated TLE.