Repolarization abnormalities on admission predict 1-year outcome in COVID-19 patients

• DOI: 10.1016/j.ijcha.2021.100912
• Publication Date: 2021-11-04T00:02:55Z
• Authors: Bert Vandenberk; Matthias M. Engelen; Greet Van De Sijpe; Jonas Vermeulen; Stefan Janssens; Thomas Vanassche; Peter Verhamme; Paul De Munter; Natalie Lorent; Rik Willems
• Keywords: Benign early repolarization

ECG abnormalities in COVID-19 have been widely reported, however data after discharge is limited. The aim was to describe on admission and following recovery of COVID-19, their associated mortality.All patients hospitalized a tertiary care hospital between March 7th July 1st 2020 with were included retrospective registry. first collected, together an the absence acute pathology. Automated measures clinical interpretations collected. Multivariate Cox regression analysis performed predict 1-year all-cause mortality.In total 420 included, which 83 (19.8%) died during follow-up period. Repolarization present 189 (45.0%). extent repolarization independent predictor mortality (HR per region 1.30, 95%CI 1.04-1.64) age (/year HR 1.06, 1.04-1.08), heart rate (/bpm 1.02, 1.01-1.03), neurological disorders 2.41, 1.47-3.93), active cancer 2.75, 1.57-4.82), CRP (per 10 mg/L 1.05, 1.02-1.08) eGFR 0.90, 0.83-0.98).In 245 (68.1%) post available. New more frequent who (4.7% versus 41.7%, p < 0.001) 8 (3.3%) had new ventricular conduction defects, none whom follow-up.The presence predicted outcome COVID-19. post-discharge mortality.