Functional network connectivity changes in children with attention‐deficit hyperactivity disorder: A resting‐state fMRI study

• DOI: 10.1016/j.ijdevneu.2019.07.003
• Publication Date: 2019-07-12T15:29:18Z
• Authors: Kaihua Jiang; Yang Yi; Lin Li; Hongxin Li; Huijuan Shen; Fangqiao Zhao; Yunpin Xu; Aibin Zheng
• Keywords: Middle frontal gyrus; Superior frontal gyrus; Limbic lobe; Medial frontal gyrus; Frontal lobe; Middle temporal gyrus; Gyrus; Parietal lobe; Superior temporal gyrus

The study aimed to investigate the pathologic mechanism of functional brain regions in attention‐deficit hyperactivity disorder (ADHD) patients through making comparisons normal and ADHD children from perspective network nodes intensity connection between bilateral hemispheres by resting‐state magnetic resonance imaging (fMRI). Thirty‐five forty‐two were examined (fMRI) scans. Data analysis was done via degree centrality (DC) voxel‐mirrored homotopic connectivity (VMHC) approaches. Compared with healthy subjects, group exhibited significantly decreased DC values right posterior cingulate gyrus, left medial superior frontal inferior parietal middle gyrus gyrus. Children also some areas increased compared children. These included cerebellar anterior lobe, occipital cortex, VMHC all revealed positive activation a range when comparing children, suggesting that scores higher lobes. This work provides new approach for examining neural mechanisms underlying ADHD, demonstrating methods enabled more comprehensive can be cross‐checked.