COVID-19 vaccines provide better protection against related pneumonia than previous symptomatic infection

• DOI: 10.1016/j.ijid.2022.04.047
• Publication Date: 2022-04-26T01:06:50Z
• Authors: Efrén Murillo-Zamora; Xóchitl Trujillo; Miguel Huerta; Mónica Ríos-Silva; José Guzmán-Esquivel; Verónica Benites-...; María Regina Ocho...; José Alejandro Gu...; Oliver Mendoza-Cano
• Keywords: Pandemic; 2019-20 coronavirus outbreak; Risk of infection

To compare, in a real-world scenario, the protective effect of vaccination and previous laboratory-confirmed symptomatic infection on risk COVID-19 pneumonia.A retrospective study was conducted 46,998 adults with were enrolled. Risk ratios (RRs) 95% confidence intervals (CIs) used to evaluate evaluated exposures pneumonia.In multiple analysis after adjusting by reinfection status, vaccinated participants at reduced developing pneumonia (RR = 0.974, CI 0.965-0.983). The association having had not significant 1.001, 0.969-1.034).Our results suggest, if later replicated, that vaccines provide better protection against than infections. Therefore, offering all eligible subjects despite past infections might be relevant reducing pandemic-related burden.