Risk factors associated with Helicobacter pylori infection in the urban population of China: A nationwide, multi-center, cross-sectional study

• DOI: 10.1016/j.ijid.2025.107890
• Publication Date: 2025-03-15T19:45:06Z
• Authors: Liang Wang; Zheng-Kang Li; Jin-Xin Lai; Yu-Ting Si; Jie Chen; Eng Guan Chua; Ling-Yan Dai; Qiong Dai; Xu-Bo Dai; Zhao-Hui Deng; Hong Du; Qi Fang; Cui Feng; Min He; Guo-Chu Hu; Yi-Zhong Hu; Hui Huang; Yan-Jiang Huang; Fen Li; Jun-Hong Li; Qi-Xin Li; Zhi-Fang Lin; Hai-Tao Liu; Ming-Bo Liu; Jin-Hua Luo; Jian-Hong Ma; Bao-Hua Man; Xiao-Jun Ru; Bo-Fu Tang; Jia-Wei Tang; Shi-Fu Tang; Yan Tian; Zeeshan Umar; Han-Dong Wang; Ji-Liang Wang; Shu-Chun Wang; Xiao-Ling Wang; Tao Wu; Dong Xia; Qing-Quan Xie; Rong-Zhang Xie; Jian-Cheng Xu; Jing Xu; Yun-Xian Ye; Gai-Ling Yuan; Quan Yuan; Li-Yan Zhang; Xin-Yu Zhang; Shu-Lei Zhao; Bin Zhou; Xing-Cheng Zhu; Wen-Bi Zou; Barry J. Marshall; Alfred Chin Yen Tay; Zhi-Bo Hou; Bing Gu
• Keywords: Cross-sectional study; Center (category theory)

To assess the risk factors associated with H. pylori infection in urban Chinese population. The study was conducted from March to November 2023, including 12,902 participants aged 18-60 years across 52 cities distributed over 26 provinces China. Risk included socioeconomic status, lifestyles, and public understanding. Univariate multivariate logistic regression analysis used calculate corrected odds ratios (ORs) 95% confidence intervals (CIs). According regression, significantly higher rates residency developing (OR 1.27, CI 1.13-1.43) undeveloped 1.15, 1.02-1.29), obesity 1.37, 1.05-1.78), alcohol consumption 1.16, 1.05-1.29), tea 1.11, 1.01-1.21), soft drink 1.24, 1.09-1.40). Conversely, individuals moderate awareness 0.79, 0.71-0.88) high 0.57, 0.48-0.69) of had lower rates. Our findings highlight importance promoting a healthy lifestyle improving understanding reducing rate bacterial pathogen