Candida auris, an emerging pathogen – Challenge in the survival of microprimies

• DOI: 10.1016/j.ijmmb.2021.03.025
• Publication Date: 2021-04-24T12:01:23Z
• Authors: Gurujala Mahadeva...; Umamaheswari Bala...; Ashok Chandrasekaran; Thangaraj Abirama...; Prakash Amboiram; Uma Sekar; R. UshaDevi
• Keywords: 0303 health sciences; Antifungal Agents; Candidiasis; Infant, Newborn; Microbial Sensitivity Tests; Candida auris; 3. Good health; 03 medical and health sciences; Infant, Extremely Low Birth Weight; Infant, Extremely Premature; Sepsis; Birth Weight; Humans

Clinical profile of extreme preterm neonates and more so, of microprimies with birth weight < 800 g is not studied till now. Our article elaborates the profile of 5 microprimies with C.auris sepsis and review of literature. The mean gestational age and birth weight were 26 weeks ± 5 days and 709 ± 64 g respectively. Mortality was 80%. The organism was susceptible to micafungin, voriconazole but was resistant to fluconazole and amphotericin. Among the 5 babies, one had organ involvement in the form of cardiac vegetation. Early identification and optimal choice of drug are crucial for better survival in C.auris sepsis.