Apoplexy of a giant clival ectopic prolactinoma: A very rare case report

• DOI: 10.1016/j.ijscr.2024.109874
• Publication Date: 2024-06-07T00:20:30Z
• Authors: Anouar Jamal; Najat Draoui; Imane Assarrar; Siham Rouf; Hanane Latrech
• Keywords: Prolactinoma; Pituitary apoplexy

Ectopic pituitary neuroendocrine tumor (EPNET) is a very rare entity, seldom with apoplexy evolution. Only three cases of intracranial ectropic were reported in the literature. We report case 45-year-old woman history amenorrhea, and headaches. Neuroimaging showed aggressive giant mass within clivus invasion sphenoidal sinus encasement internal carotid arteries an empty sella. Endocrinology work-up revealed exceedingly high level prolactin surprisingly without galactorrhea. Immunohistochemical analysis after endonasal biopsy confirmed diagnosis prolactinoma. One month Cabergoline initiation, ectopic occurred. Conservational management decrease cabergoline dose was performed. This article highlights data from various literature addition to our confirm extreme rarity as complication EPNET. Pituitary extremely rare. Therefore, unusual localization tumor, thorough follow-up necessary detect complications ensure early management.