Huanglian Jiedu Decoction enhances the stability of atherosclerotic plaques through SLC2A1-mediated efferocytosis

• DOI: 10.1016/j.intimp.2024.112834
• Publication Date: 2024-08-07T02:53:19Z
• Authors: Guiting Zhou; Liwen Lin; Shushu Wang; Mingxin Dong; Kachun Lu; Yuling Zhang; Zhichao Lin; Jinhai Lin; Wei Wu; Rui Peng; Chuanjin Luo
• Keywords: efferocytosis; Oil Red O

Atherosclerotic (AS) plaques require a dense necrotic core and robust fibrous cap to maintain stability. While previous studies have indicated that the traditional Chinese medicine Huang Lian Jie Du Decoction (HLJDD) possesses capability stabilize AS plaques, underlying mechanisms remain obscure. This study aims delve deeper into potential by which HLJDD improves through an integrated research strategy.