The genomic characteristics affect phenotypic diversity from the perspective of genetic improvement of economic traits

• DOI: 10.1016/j.isci.2023.106426
• Publication Date: 2023-03-17T02:20:54Z
• Authors: Jinyu Chu; Yunlong Ma; Hui Song; Qianqian Zhao; Xiaoran Wei; Yiyuan Yan; Shijie Fan; Baogui Zhou; Shijun Li; Chunyan Mou
• Keywords: Polygene; Indel; Phenotypic trait

The genetic improvement of economic traits suggests that chicken is an excellent model for exploring the changes and molecular mechanisms underlying phenotypic diversity artificial selection. Here, sequencing data including 477 samples from 25 breeds worldwide were used to reveal genomic patterns domestication. We analyzed 7.4 Tb clean with 14.8× per individual identify 23,504,766 SNPs, 3,289,782 InDels, 27,027 SVs. analysis indicates high-intensity selection would accelerate population differentiation. also found human-driven are controlled by polygenes major genes, such as primary candidates SOX5 IGF1 body size, NEDD4 sperm storage capacity. Our findings provide important reference understanding how shape phenotypes in livestock.