Inflammasome-mediated glucose limitation induces antibiotic tolerance in Staphylococcus aureus

• DOI: 10.1016/j.isci.2023.107942
• Publication Date: 2023-09-17T13:38:26Z
• Authors: Jenna E. Beam; Nikki J. Wagner; Kuan-Yi Lu; Joshua B. Parsons; Vance G. Fowler; Sarah E. Rowe; Brian P. Conlon
• Keywords: Human pathogen; Multidrug tolerance

is a leading human pathogen that frequently causes relapsing infections. The failure of antibiotics to eradicate infection contributes relapse. Host-pathogen interactions have substantial impact on antibiotic susceptibility and the formation tolerant cells. In this study, we interrogate how major