Phagosomal granulocytic ROS in septic patients induce the bacterial SOS response

• DOI: 10.1016/j.isci.2024.109825
• Publication Date: 2024-04-26T16:50:15Z
• Authors: Stecy Chollet; Ana Catalina Hern...; Thomas Daix; Margaux Gaschet; Bruno François; Christophe Piguet; Nathalie Gachard; Sandra Da Re; Robin Jeannet; Marie-Cécile Ploy
• Keywords: Inflammatory response

Septic patients with worst clinical prognosis have increased circulating immature granulocytes (IG), displaying limited phagocytosis and reactive oxygen species (ROS) production. Here, we developed an