Frontal gamma-alpha ratio reveals neural oscillatory mechanism of attention shifting in tinnitus

• DOI: 10.1016/j.isci.2025.111929
• Publication Date: 2025-02-05T00:03:33Z
• Authors: Xueji Feng; Xiaoyu Bao; Haiyun Huang; Zijian Wang; Wen Hu; Chenxi Xue; Zhiqing Song; Yuexin Cai; Qiyun Huang; Yuanqing Li
• Keywords: Alpha (finance)

In clinical practice, the symptoms of tinnitus patients can be temporarily alleviated by diverting their attention away from disturbing sounds. However, precise mechanisms through which this alleviation occurs are still not well understood. Here, we aimed to directly evaluate role in conducting distraction tasks with multilevel loads and resting-state tests among 52 adults healthy controls. We demonstrated that abnormal neural oscillations subjects, reflected an altered gamma/alpha ratio index frontal lobe, could regulated shifting a linear manner for regulatory effect increased load distraction. Quantitative measures regulation significantly correlated symptom severity. Altogether, our work provides proof-of-concept perception lays solid foundation support evidence-based applications interventions tinnitus.