Road Traffic Noise and Incidence of Primary Hypertension

• DOI: 10.1016/j.jacadv.2023.100262
• Publication Date: 2023-03-22T18:53:21Z
• Authors: Jing Huang; Teng Yang; John Gulliver; Anna L. Hansell; Mohammad Mamouei; Yutong Samuel Cai; Kazem Rahimi

The quality of evidence regarding the associations between road traffic noise and hypertension is low due to limitations cross-sectional study design, role air pollution remains be further clarified. purpose this was evaluate long-term exposure with incident primary hypertension; we conducted a prospective population-based analysis in UK Biobank. Road estimated at baseline residential address using common assessment method model. Incident ascertained through linkage medical records. Cox proportional hazard models were used estimate ratios (HRs) for association an analytical sample size over 240,000 participants free baseline, adjusting covariates determined via directed acyclic graph. During median 8.1 years follow-up, 21,140 (International Classification Diseases-10th Revision [ICD-10]: I10) ascertained. HR 10 dB[A] increment mean weighted average 24-hour level (Lden) 1.07 (95% CI: 1.02-1.13). A dose-response relationship found, 1.13 1.03-1.25) Lden >65 vs ≤55 (P trend <0.05). all robust adjustment fine particles (PM2.5) nitrogen dioxide (NO2). Furthermore, high both associated highest risk. Long-term increased incidence hypertension, effect estimates stronger presence higher pollution.