Sex-Based Differences in Patients With Left Ventricular-Assisted Devices and Strokes

• DOI: 10.1016/j.jacadv.2023.100817
• Publication Date: 2024-01-11T03:18:24Z
• Authors: Salma Zook; Otito Ojukwu; Safi U. Khan; Abdul Mannan Khan...; Harveen K. Lamba; Katelyn E. Ingram; Mahwash Kassi

Sex-based differences in clinical outcomes among patients with stroke related to left ventricular assist devices (LVADs) are not well described. In this study, the authors examined characteristics and men women who had a during LVAD hospitalization. The National Inpatient Sample from 2010 2019 was used identify Outcomes of interest include inpatient mortality complications vs women. Weighted logistic regression determine association sex outcomes. Adjustments were made for age Elixhauser comorbidity index. total, 35,820 underwent implantation (77% men), 6.12% (n = 2,192) experienced stroke. Women younger than (mean 51 years 59 years, P < 0.001). Men strokes higher burden comorbidities While there no odds ischemic stroke, hemorrhagic compared (OR: 1.49 [95% CI: 1.02-2.18]). Mortality significantly those without Between 2019, rates increased men, while trend remained variable national cohort, worsening trends over last decade fewer implants incidence Understanding factors that contribute sex-related outcome disparities is crucial addressing these diverging trends.