Safety and Effectiveness of Bypassing Oral Immunotherapy Buildup With an Initial Phase of Sublingual Immunotherapy for Higher-Risk Food Allergy

• DOI: 10.1016/j.jaip.2024.02.024
• Publication Date: 2024-02-27T17:25:49Z
• Authors: Lianne Soller; Brock A. Williams; Raymond Mak; Tiffany Wong; Stephanie C. Erdle; Alanna Chomyn; Brittany Tetreault; Kelly Morrison; Lisa Gaudet; Edmond S. Chan
• Keywords: Sublingual Immunotherapy; Oral immunotherapy; Slit; Sublingual administration

Because of its favorable safety, sublingual immunotherapy (SLIT) for food allergy has been proposed as an alternative treatment those in whom oral (OIT) is higher risk-older children, adolescents, adults, and with a history severe reactions. Although safe, SLIT shown to be less effective than OIT.