Silicon dioxide nanoparticles decorated on graphene oxide nanosheets and their application in poly(l-lactic acid) scaffold

• DOI: 10.1016/j.jare.2022.08.017
• Publication Date: 2022-09-07T07:10:32Z
• Authors: Cijun Shuai; Feng Yang; Yang Shuai; Shuping Peng; Shijie Chen; Youwen Deng; Pei Feng
• Keywords: Silicon dioxide; Surface Modification; Selective laser sintering

The aggregation of graphene oxide (GO) is considered as main challenge, although GO possesses excellent mechanical properties which arouses widespread attention reinforcement for polymers.In this study, silicon dioxide (SiO2) nanoparticles were decorated onto surface nanosheets through in situ growth method promoting dispersion poly(l-lactic acid) (PLLA) bone scaffold.Hydroxyl and carboxyl functional groups provided sites SiO2 nucleation, grew with hydrolysis polycondensation tetraethyl orthosilicate (TEOS) finally formed covalent bonds. Then, the GO@ nanocomposite was blended PLLA fabrication scaffold by selective laser sintering (SLS).The results indicated that obtained distributed relatively uniformly on under TEOS concentration 0.10 mol/L (GO@SiO2-10), covering could increase interlayer distance from 0.799 nm to 0.894 nm, thus reducing van der Waals forces between facilitating dispersion. Tensile compressive strength containing GO@SiO2 hybrids significantly enhanced, especially GO@SiO2-10 enhancement 30.95 % tensile 66.33 compared GO. Additionally, cell adhesion fluorescence experiments demonstrated cytocompatibility scaffold.The good enhances scaffold, making it a potential candidate tissue engineering applications.