Black bean (Phaseolus vulgaris L.) protein hydrolysates reduce acute postprandial glucose levels in adults with prediabetes and normal glucose tolerance

• DOI: 10.1016/j.jff.2023.105927
• Publication Date: 2023-11-30T13:03:03Z
• Authors: Luis Mojica; Andrea Susana Ram...; Oscar Abel Sánche...; Armando Gómez-Ojeda; Claudia Luevano-C...
• Keywords: Prediabetes; Glucose tolerance test

This study evaluated the acute effect of black bean protein hydrolysate (BPH) on postprandial glucose and insulin levels in adults with normal tolerance (NGT) or prediabetes. First, an silico predictive digestion was performed twenty peptides identified BPH. Then, 28 NGT prediabetes were randomized to a parallel double-blind, placebo-controlled trial. Following consent, participants randomly assigned one two groups, placebo, 5 g To evaluate effects BPH, oral test administered, blood samples collected at 60, 120, 150 min. In BPH group, area under curve for glucose, 120 min statistically lower compared placebo group (p = 0.04, p 0.02). this study, had lowering after subjects