Unveiling a high-risk epidemic clone (ST 357) of ‘Difficult to Treat Extensively Drug-Resistant’ (DT-XDR) Pseudomonas aeruginosa from a burn patient in Bangladesh: A resilient beast revealing coexistence of four classes of beta lactamases

• DOI: 10.1016/j.jgar.2023.11.014
• Publication Date: 2023-12-19T07:24:23Z
• Authors: Spencer Mark Mondol; Md. Rafiul Islam; Nadira Naznin Rakhi; Shahriar Kabir Sh...; Israt Islam; Jannatul Ferdous ...; Amiruzzaman; Hussain Md. Shahj...; Donald James Gomes; Md. Mizanur Rahaman
• Keywords: Multilocus sequence typing; Resistome; Efflux; clone (Java method)

Pseudomonas aeruginosa (P. aeruginosa) stands out as a key culprit in the colonization of burn wounds, instigating grave infections heightened severity. In this study, we have performed comparative whole genome analysis difficult to treat extensively drug resistant P. isolated from patient order elucidate genomic diversity, molecular patterns, mechanisms and genes responsible for conferring antimicrobial resistance virulence.