EASL Clinical Practice Guidelines on prevention and management of bleeding and thrombosis in patients with cirrhosis

• DOI: 10.1016/j.jhep.2021.09.003
• Publication Date: 2022-03-15T02:01:07Z
• Authors: Erica Villa; Marcello Bianchini; Annabel Blasi; Alban Denys; Edoardo G. Giannini; Andrea de Gottardi; Ton Lisman; Emmanuelle de Rau...; Cristina Ripoll; Pierre-Emmanuel R...
• Keywords: Liver Cirrhosis; Hemostasis; 03 medical and health sciences; 0302 clinical medicine; Anticoagulants; Humans; Hemorrhage; Thrombosis; Venous Thromboembolism; 3. Good health

The prevention and management of bleeding and thrombosis in patients with cirrhosis poses several difficult clinical questions. These Clinical Practice Guidelines have been developed to provide practical guidance on debated topics, including current views on haemostasis in liver disease, controversy regarding the need to correct thrombocytopenia and abnormalities in the coagulation system in patients undergoing invasive procedures, and the need for thromboprophylaxis in hospitalised patients with haemostatic abnormalities. Multiple recommendations in this document are based on interventions that the panel feels are not useful, even though widely applied in clinical practice.