Active viral shedding in a vaccinated hospitalized patient infected with the delta variant (B.1.617.2) of SARS-CoV-2 and challenges of de-isolation

• DOI: 10.1016/j.jiph.2022.04.011
• Publication Date: 2022-04-28T16:04:05Z
• Authors: Abeer N. Alshukairi; Awad Al-Omari; Jaffar A. Al-Tawfiq; Sherif A. El-Kafrawy; Mai M. El-Daly; Ahmed M. Hassan; Arwa A. Faizo; Thamir A. Alandijany; Ashraf Dada; Mohammed F. Saeedi; Fatma S. Alhamlan; Mohammad K. Al Hroub; Ismael Qushmaq; Esam I. Azhar
• Keywords: Viral Shedding; Isolation; Immunosuppression; Viral Pneumonia; 2019-20 coronavirus outbreak

In the era of SARS-CoV-2 variants and COVID-19 vaccination, duration infectious viral shedding isolation in post vaccine breakthrough infections is challenging depends on disease severity. The current study described a case Delta variant pneumonia requiring hospitalization. patient received two doses BNT162b2 vaccines, he had positive cultures 12 days symptom onset. time between second dose infection was 6 months. While immunosuppression known risk factor for prolonged shedding, age vaccination are important factors that warrant further studies.