Green synthesis, characterization and biomedical potential of Ag@Au core–shell noble metal nanoparticles

• DOI: 10.1016/j.jksus.2022.102000
• Publication Date: 2022-03-29T16:28:56Z
• Authors: Mona S. Alwhibi; Khalid M.O. Ortashi; Awatif A. Hendi; M.A. Awad; Dina A. Soliman; Mohamed El-Zaidy
• Keywords: Chloroauric acid; Bimetallic strip; Noble metal; Silver nitrate; Silver nanoparticle

In the current times, nanotechnology has emerged as a field that promises scientific advancement with manipulation, improvement, and application of near-atomic scale materials.Bimetallic nanoparticles (NPs) have been explored for their wide range applications owing to multi-functionalilty. The present study included synthesis bimetallic silver@gold (Ag@Au) NPs from aqueous chloroauric acid (HAuCl4) silver nitrate (AgNO3) making use 'green chemistry' extract Acacia nilotica husk reducing capping agent. formed were characterized by various spectrometry electron microscopy techniques devices, including ultraviolet–visible spectroscopy (UV/VIS), transmission (TEM), energy-dispersive X-ray (EDS) attached scanning (SEM), Fourier-transform infrared (FTIR), particle size distribution was analyzed dynamic light scattering (DLS) technique. FTIR results identified functional groups are involved in interact biomolecules surfaces through extensive screening on synthesized colloidal NPs. core – shell had mean monodispersity index (PDI) values 0.223 61 nm, respectively. TEM micrographs clearly indicated Au coating surrounding Ag size, shapes homogeneous uniform. Anticancer activity Ag@Au using MTT assay; recorded cell viability 500 μg/ml cytotoxicity (IC50) 74.6 ± 7.43 µg/ml HeLa line. This anticancer opens window cancer therapy other biomedical applications.